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Preclinical Development of Complement C5aR Antagonists for the Treatment of Motor Neuron Disease

Preclinical Development of Complement C5aR Antagonists for the Treatment of Motor Neuron Disease
补体 C5aR 拮抗剂治疗运动神经元疾病的临床前开发
批准号:
nhmrc : 1118881
负责人:
A/Pr Trent Woodruff
金额:
$40.53万
依托单位国家:
澳大利亚
项目类别:
Development Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2019-12-31

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中文摘要
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英文摘要
There is no cure for Motor Neuron Disease (MND) resulting in 2 Australian’s dying each day. Modification of the inflammation is one potential means of slowing MND. Our research team has identified a new series of potent anti-inflammatory compounds that may have potential to treat this disease. Our project will test these compounds in animal models of MND, and validate their usefulness in human MND samples. Ultimately, this work may contribute to the discovery of a new treatment for MND.
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