Therapeutic targeting of neuroinflammation to slow the progression of neurodegenerative disease

以神经炎症为治疗目标以减缓神经退行性疾病的进展

• 批准号: nhmrc : 1105420
• 负责人: A/Pr Trent Woodruff
• 金额: $ 31.94万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/therapeutic-targeting-neuroinflammation-neurodegenerative-disease/662828
• 关键词: Therapeutic; targeting; neuroinflammation; slow; progression

My research has identified key components of our immune system, that can worsen disease in conditions such as Parkinson’s disease and motor neuron disease. I hope that exploring these components in animal models, and patients suffering from these diseases, my group can identify new therapeutic drug candidates that can be progressed in clinical trials. Ultimately, this may lead to new treatments to reduce disease burden in patients suffering from these neurodegenerative conditions.

我的研究已经确定了我们免疫系统的关键组成部分，这些组成部分可能会使帕金森病和运动神经元疾病等疾病恶化。我希望通过在动物模型和患有这些疾病的患者中探索这些成分，我的团队能够找到可以在临床试验中取得进展的新候选治疗药物。最终，这可能会带来新的治疗方法，以减轻患有这些神经退行性疾病的患者的疾病负担。