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Targeting the Complement Cascade: A Novel Therapeutic Strategy for Metastatic Melanoma

Targeting the Complement Cascade: A Novel Therapeutic Strategy for Metastatic Melanoma
针对补体级联:转移性黑色素瘤的新型治疗策略
批准号:
nhmrc : GNT1103951
负责人:
A/Pr Trent Woodruff
金额:
$54.65万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --

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中文摘要
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英文摘要
The incidence of melanoma is increasing world-wide, and Queensland has the highest rate of melanoma in the world. Despite advances in treatment, the 3-year survival rate for metastatic melanoma remains extremely low. This project builds on our recent research demonstrating a role for a key component of the innate immune system (complement C3a) in melanoma growth. Specifically we seek to investigate the potential of C3a as a therapeutic target for metastatic melanoma.
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Harnessing the Innate Immune System to Target Cancer: A Novel Immunotherapeutic Strategy for Solid Tumours
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    nhmrc : GNT1155938
  • 项目类别:
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    $65.13万
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    A/Pr Trent Woodruff
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Preclinical Development of Complement C5aR Antagonists for the Treatment of Motor Neuron Disease
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    $40.53万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Trent Woodruff
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Preclinical Development of Complement C5aR Antagonists for the Treatment of Motor Neuron Disease
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    nhmrc : GNT1118881
  • 项目类别:
    Development Grants
  • 资助金额:
    $59.33万
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    2017
  • 负责人:
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Therapeutic targeting of neuroinflammation to slow the progression of neurodegenerative disease
  • 批准号:
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  • 项目类别:
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  • 资助金额:
    $46.37万
  • 财政年份:
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  • 负责人:
    A/Pr Trent Woodruff
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国内基金
海外基金
Complement C6蛋白抑制DNA损伤修复增敏甲状腺乳头状癌放射性碘治疗的作用及其机制
  • 批准号:
    --
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    30万元
  • 批准年份:
    2022
  • 负责人:
    刘宇佳
  • 依托单位: