Preclinical Development of Complement C5aR Antagonists for the Treatment of Motor Neuron Disease
补体 C5aR 拮抗剂治疗运动神经元疾病的临床前开发
基本信息
- 批准号:nhmrc : GNT1118881
- 负责人:
- 金额:$ 59.33万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Development Grants
- 财政年份:2017
- 资助国家:澳大利亚
- 起止时间:2017-01-01 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
There is no cure for Motor Neuron Disease (MND) resulting in 2 Australian’s dying each day. Modification of the inflammation is one potential means of slowing MND. Our research team has identified a new series of potent anti-inflammatory compounds that may have potential to treat this disease. Our project will test these compounds in animal models of MND, and validate their usefulness in human MND samples. Ultimately, this work may contribute to the discovery of a new treatment for MND.
运动神经元疾病(MND)无法治愈,每天有2名澳大利亚人死亡。炎症的改变是减缓MND的一种潜在手段。我们的研究团队已经发现了一系列新的强效抗炎化合物,可能有潜力治疗这种疾病。我们的项目将在MND动物模型中测试这些化合物,并验证它们在人类MND样品中的有用性。最终,这项工作可能有助于发现MND的新治疗方法。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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A/Pr Trent Woodruff其他文献
A/Pr Trent Woodruff的其他文献
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{{ truncateString('A/Pr Trent Woodruff', 18)}}的其他基金
Harnessing the Innate Immune System to Target Cancer: A Novel Immunotherapeutic Strategy for Solid Tumours
利用先天免疫系统靶向癌症:实体瘤的新型免疫治疗策略
- 批准号:
nhmrc : GNT1155938 - 财政年份:2019
- 资助金额:
$ 59.33万 - 项目类别:
Development Grants
Preclinical Development of Complement C5aR Antagonists for the Treatment of Motor Neuron Disease
补体 C5aR 拮抗剂治疗运动神经元疾病的临床前开发
- 批准号:
nhmrc : 1118881 - 财政年份:2017
- 资助金额:
$ 59.33万 - 项目类别:
Development Grants
Targeting the Complement Cascade: A Novel Therapeutic Strategy for Metastatic Melanoma
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nhmrc : GNT1103951 - 财政年份:2016
- 资助金额:
$ 59.33万 - 项目类别:
Project Grants
Therapeutic targeting of neuroinflammation to slow the progression of neurodegenerative disease
以神经炎症为治疗目标以减缓神经退行性疾病的进展
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nhmrc : GNT1105420 - 财政年份:2016
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$ 59.33万 - 项目类别:
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Therapeutic targeting of neuroinflammation to slow the progression of neurodegenerative disease
以神经炎症为治疗目标以减缓神经退行性疾病的进展
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nhmrc : 1105420 - 财政年份:2016
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Targeting the Complement Cascade: A Novel Therapeutic Strategy for Metastatic Melanoma
针对补体级联:转移性黑色素瘤的新型治疗策略
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nhmrc : 1103951 - 财政年份:2016
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$ 59.33万 - 项目类别:
Project Grants
Complement C5a Receptors , Placental Inflammation and Reproductive Impairment.
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- 资助金额:
$ 59.33万 - 项目类别:
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The Role of the Complement System in Neurodegeneration and the Therapeutic Potential of Complement Inhibition
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- 批准号:
nhmrc : 519700 - 财政年份:2008
- 资助金额:
$ 59.33万 - 项目类别:
Career Development Fellowships
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