Complement C5a Receptors , Placental Inflammation and Reproductive Impairment.

补充 C5a 受体、胎盘炎症和生殖障碍。

• 批准号: nhmrc : 569693
• 负责人: A/Pr Trent Woodruff
• 金额: $ 68.36万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/complement-c5a-receptors-reproductive-impairment/82867
• 关键词: Complement; C5a; Receptors; Placental; Inflammation

We are investigating how mothers may have health difficulties during pregnancy, such as high blood pressure, and how this can affect their fetuses' health. There is emerging evidence that an unhealthy placenta during pregnancy can greatly affect fetal development, and it seems that inflammation in the placenta during pregnancy may be a key factor in reducing fetal growth, resulting in low birth weight infants. Our studies are aimed at developing new treatments for this.

我们正在调查母亲在怀孕期间如何出现健康问题，如高血压，以及这如何影响胎儿的健康。有新的证据表明，怀孕期间不健康的胎盘会极大地影响胎儿的发育，而且怀孕期间胎盘的炎症可能是降低胎儿生长的关键因素，导致低出生体重婴儿。我们的研究旨在开发新的治疗方法。