Dynamic modelling of the oral, pharyngeal and laryngeal complex for biomedical applications

用于生物医学应用的口腔、咽部和喉部复合体的动态建模

• 批准号: 350630-2007
• 负责人: Fels, Sidney
• 金额: $ 14.96万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Strategic Projects - Group
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=402140
• 关键词: Dynamic; modelling; oral; pharyngeal; laryngeal

Computer simulation of human anatomy is expected to become an increasingly useful tool in medical research, diagnosis, and treatment. This project will improve the state of the art of such simulation by creating a complete computer model of the mouth and throat region, and using it to study several important medical disorders. These include sleep apnea (interrupted breathing during sleep), which afflicts an estimated twelve million Americans and can lead to complications such as heart disease; difficulty in swallowing as caused by stroke; and treating impairments of chewing and swallowing caused by surgery. Treatment of these conditions can be difficult because they involve complicated interactions between the nerves, muscles, and tissues of the mouth-throat region. Our model will help us better understand these interactions.

人体解剖学的计算机模拟有望成为医学研究、诊断和治疗中越来越有用的工具。该项目将通过创建口腔和咽喉区域的完整计算机模型，并使用它来研究几种重要的医学疾病，从而提高这种模拟技术的水平。其中包括睡眠呼吸暂停（睡眠时呼吸中断），据估计有1200万美国人患有这种疾病，并可能导致心脏病等并发症；吞咽困难：因中风引起的吞咽困难；治疗手术造成的咀嚼和吞咽障碍。这些疾病的治疗可能很困难，因为它们涉及神经、肌肉和口腔-喉咙区域组织之间复杂的相互作用。我们的模型将帮助我们更好地理解这些相互作用。