Therapeutic potential of transforming growth factor-beta proteins for the diagnosis and treatment of female infertility

转化生长因子-β蛋白在诊断和治疗女性不孕症中的治疗潜力

• 批准号: nhmrc : 1121504
• 负责人: A/Pr Craig Harrison
• 金额: $ 64.44万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/therapeutic-potential-transforming-female-infertility/946747
• 关键词: Therapeutic; potential; transforming; growth; factor

We discovered and manufactured a growth factor produced uniquely by the egg. We named this growth factor cumulin. It is a powerful regulator of ovarian function and egg quality. This project will study the basic mechanisms of how cumulin works in the ovary. We will then develop an assay to measure it as a biomarker of human egg quality and quantity. New approaches in fertility preservation for cancer survivors will be developed using cumulin.

我们发现并制造了一种由卵子产生的生长因子。我们将这种生长因子命名为cumulin。它是卵巢功能和卵子质量的强大调节剂。本项目将研究累积蛋白在卵巢中的基本作用机制。然后，我们将开发一种检测方法，将其作为人类卵子质量和数量的生物标志物进行测量。将使用cumulin开发癌症幸存者生育力保存的新方法。