Understanding determinant selection in autoimmune diseases

了解自身免疫性疾病的决定因素选择

• 批准号: nhmrc : 1044215
• 负责人: Prof Anthony Purcell
• 金额: $ 45.79万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-determinant-selection-autoimmune-diseases/111641
• 关键词: Understanding; determinant; selection; autoimmune; diseases

Understanding what the immune system perceives during infection or in autoimmunity is key to the development of improved vaccines and therapies for a variety of human diseases. This proposal builds on leading research into the definition of targets of immunity in autoimmune diseases using cutting edge proteomic technologies. The proposal focuses on type 1 diabetes, multiple sclerosis, lupus and rheumatoid arthritis and will delineate candidate therapeutic molecules.

了解免疫系统在感染或自身免疫过程中的感知是开发各种人类疾病的改进疫苗和疗法的关键。该提案建立在使用尖端蛋白质组学技术定义自身免疫性疾病免疫靶点的领先研究基础上。该提案的重点是1型糖尿病，多发性硬化症，狼疮和类风湿性关节炎，并将划定候选治疗分子。