Understanding the pathophysiology of schizophrenia, major depressive disorder and bipolar disorder as a basis for improving treatments

了解精神分裂症、重度抑郁症和双相情感障碍的病理生理学，作为改善治疗的基础

• 批准号: nhmrc : 1002240
• 负责人: Prof Brian Dean
• 金额: $ 53.62万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-pathophysiology-schizophrenia-improving-treatments/108791
• 关键词: Understanding; pathophysiology; schizophrenia; major; depressive

The Applicant seeks to understand the causes of the schizophrenia, bipolar disorder and major depressive disorder, which affect over 20% of the Australian population. This research is important as drug design, based on chemical remodelling, has not significantly advanced initial breakthroughs in treating psychiatric disorders and there is now a widespread belief that new drugs will only come from understand their causes.

申请人试图了解精神分裂症、双相情感障碍和重度抑郁症的原因，这些疾病影响着澳大利亚20%以上的人口。这项研究很重要，因为基于化学重塑的药物设计在治疗精神疾病方面并没有取得重大突破，现在人们普遍认为，只有了解其原因，才能开发出新药。