Understanding the physiological role of COUP-TF orphan nuclear receptors in skeletal muscle.
Understanding the physiological role of COUP-TF orphan nuclear receptors in skeletal muscle.
批准号:
nhmrc : 569742
负责人:
Prof George Muscat
金额:
$30.33万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31
中文摘要
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英文摘要
COUP-TF is a protein expressed in skeletal muscle, a tissue that accounts for ~40% of the body mass and energy expenditure, and is a major site of nutrient metabolism. COUP-TF is a member of the nuclear hormone receptor (NR) superfamily. These proteins respond to physiological signals, and are targets of pharmaceuticals for the treatment of inflammation, metabolic and endorcrine disorders. Our project is directed toward understanding the role of COUP-TF in the context of metabolism and obesity.
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会议论文
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NR1 nuclear hormone receptors, and skeletal muscle metabolism: insights into dyslipidemia and metabolic disease.
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Research Fellowship - Grant ID:401504
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国内基金
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羊草子株出生、发育及成穗的生理与分子机制
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