Biomolecular imaging in fundamental cell and molecular biology research

基础细胞和分子生物学研究中的生物分子成像

• 批准号: 390389-2010
• 负责人: Drobetsky, Elliot
• 金额: $ 5.63万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=443183
• 关键词: Biomolecular; imaging; fundamental; cell; molecular

Our DNA provides the genetic blueprint for the production of thousands of different proteins that in turn mediate all of the biochemical reactions in our bodies. The current equipment grant application originates from a group of scientists whose fundamental research programs absolutely depend upon the ability, under various experimental conditions, to study the expression levels of particular biomolecules (such as proteins and DNA) in biological systems. Thus, funding is requested for the purchase of a "biomolecular imager with fluorescence capability" which constitutes a sensitive, reliable, and highly-flexible instrument for identifying and quantifying individual biomolecules in cultured cells as well as in tissue samples.

我们的DNA提供了生产数千种不同蛋白质的遗传蓝图，这些蛋白质反过来又介导了我们体内的所有生化反应。目前的设备资助申请来自一群科学家，他们的基础研究计划完全取决于在各种实验条件下研究生物系统中特定生物分子（如蛋白质和DNA）的表达水平的能力。因此，需要资金购买“具有荧光能力的生物分子成像仪”，这是一种灵敏、可靠和高度灵活的仪器，用于识别和量化培养细胞以及组织样本中的单个生物分子。