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The role of SUMO modifications on estrogen receptor function by kinase signaling pathways

The role of SUMO modifications on estrogen receptor function by kinase signaling pathways
SUMO 修饰通过激酶信号通路对雌激素受体功能的作用
批准号:
311761-2007
负责人:
Tremblay, André
金额:
$1.91万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-01-01 至 2011-12-31

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英文摘要
Recently, the identification of SUMOylation, the process by which SUMO, a small ubiquitin-like modifier, is covalently linked to target proteins, has emerged as a new protein modification that regulates the function of an increasing number of transcription factors. The functional consequences of SUMOylation are not understood at the molecular level, but with recent observations that nuclear receptors were reported to be SUMOylated, this raises the interesting possibility that SUMOylation may serve as a novel mechanism by which hormonal signaling pathways may regulate transcription.
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The role of a novel SUMO conjugation process on nuclear receptor function and gene transcription
  • 批准号:
    RGPIN-2019-05580
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.06万
  • 财政年份:
    2022
  • 负责人:
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  • 依托单位:
The role of a novel SUMO conjugation process on nuclear receptor function and gene transcription
  • 批准号:
    RGPIN-2019-05580
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.06万
  • 财政年份:
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  • 负责人:
    Tremblay, André
  • 依托单位:
The role of a novel SUMO conjugation process on nuclear receptor function and gene transcription
  • 批准号:
    RGPIN-2019-05580
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.06万
  • 财政年份:
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  • 负责人:
    Tremblay, André
  • 依托单位:
Multimode determination of gene transcription and metabolic labeling
  • 批准号:
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  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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  • 负责人:
    Tremblay, André
  • 依托单位:
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