Retromer directs membrane protein trafficking within the endosome

逆转录酶指导内体内膜蛋白的运输

• 批准号: DP120103930
• 负责人: A/Prof Rohan Teasdale
• 金额: $ 23.64万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120103930
• 关键词: Retromer; directs; membrane; protein; trafficking

The exposure of proteins to the extracellular environment is dependent on how the travel through the various regions of the cell. The work will lead to a richer understanding of how this process is regulated by protein complexes. These complexes act within cells to drive the formation of membrane transport tubules containing cargo molecules.

蛋白质在细胞外环境中的暴露取决于蛋白质如何通过细胞的不同区域。这项工作将使人们对蛋白质复合体如何调控这一过程有更丰富的理解。这些复合体在细胞内作用，驱动含有货物分子的膜运输小管的形成。