课题基金 / 基金详情

Organising Intracellular Compartments by Formation of Transport Carriers.

Organising Intracellular Compartments by Formation of Transport Carriers.
通过形成运输载体来组织细胞内区室。
批准号:
DP210103017
负责人:
A/Prof Rohan Teasdale
金额:
$38.61万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2023-12-31

项目摘要

项目成果

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中文摘要
翻译
这个项目的目的是研究产生载体的细胞组件,这些载体在细胞内的隔间之间运输材料。对蛋白质进行分类并将其送到正确位置的过程是理解单个蛋白质在细胞内移动时如何发挥作用的关键基本机制。产生的关于细胞如何通过蛋白质在内体细胞内隔间之间移动来组织自己的知识将提供显著的好处,因为它将增强我们理解这一保守的细胞途径的能力,这一途径确保了所有细胞过程的完整性,包括信号、通信、内稳态和发育。
英文摘要
This project aims to investigate the cellular components which generate carriers that transport material between compartments within the cell. The process of sorting proteins and sending them to the right place is a fundamental mechanism critical to understand how individual proteins function as the move around within cells. The generated knowledge about how cells organise themselves through the movement of proteins between endosomal intracellular compartments will provide significant benefits by enhancing our capacity to understand this conserved cellular pathway which ensures the integrity of all cellular processes including signalling, communication, homeostasis and development.
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Defining the membrane protein cargo transported by Retromer
  • 批准号:
    DP160101573
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $32.88万
  • 财政年份:
    2016
  • 负责人:
    A/Prof Rohan Teasdale
  • 依托单位:
Formation of the Chlamydial Inclusion Requires Host Trafficking Pathways
  • 批准号:
    DP150100364
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $25.55万
  • 财政年份:
    2015
  • 负责人:
    A/Prof Rohan Teasdale
  • 依托单位:
Retromer directs membrane protein trafficking within the endosome
  • 批准号:
    DP120103930
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $23.64万
  • 财政年份:
    2012
  • 负责人:
    A/Prof Rohan Teasdale
  • 依托单位:
The molecular basis of macropinocytosis in mammalian cells: the composition of endosome proteins and their function
  • 批准号:
    DP0771706
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $18.25万
  • 财政年份:
    2007
  • 负责人:
    A/Prof Rohan Teasdale
  • 依托单位:
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