Organising Intracellular Compartments by Formation of Transport Carriers.

通过形成运输载体来组织细胞内区室。

• 批准号: DP210103017
• 负责人: A/Prof Rohan Teasdale
• 金额: $ 38.61万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210103017
• 关键词: Organising; Intracellular; Compartments; Formation; Transport

This project aims to investigate the cellular components which generate carriers that transport material between compartments within the cell. The process of sorting proteins and sending them to the right place is a fundamental mechanism critical to understand how individual proteins function as the move around within cells. The generated knowledge about how cells organise themselves through the movement of proteins between endosomal intracellular compartments will provide significant benefits by enhancing our capacity to understand this conserved cellular pathway which ensures the integrity of all cellular processes including signalling, communication, homeostasis and development.

该项目旨在研究产生载体的细胞成分，这些载体在细胞内的隔室之间运输材料。将蛋白质分类并将其发送到正确的位置的过程是理解单个蛋白质如何在细胞内移动的基本机制。所产生的关于细胞如何通过蛋白质在内体细胞内区室之间的运动来组织自己的知识将通过增强我们理解这种保守的细胞途径的能力来提供显着的益处，这种保守的细胞途径确保所有细胞过程的完整性，包括信号传导，通信，稳态和发育。