Organising Intracellular Compartments by Formation of Transport Carriers.

该项目旨在研究产生载体的细胞成分，这些载体在细胞内的隔室之间运输物质。对蛋白质进行分类并将其送到正确位置的过程是一种基本机制，对于理解单个蛋白质在细胞内移动时如何发挥作用至关重要。所产生的关于细胞如何通过蛋白质在内体细胞内区室之间的运动来组织自己的知识将通过增强我们理解这种保守的细胞途径的能力提供显著的好处，这种途径确保了所有细胞过程的完整性，包括信号传导、通信、稳态和发育。

This project aims to investigate the cellular components which generate carriers that transport material between compartments within the cell. The process of sorting proteins and sending them to the right place is a fundamental mechanism critical to understand how individual proteins function as the move around within cells. The generated knowledge about how cells organise themselves through the movement of proteins between endosomal intracellular compartments will provide significant benefits by enhancing our capacity to understand this conserved cellular pathway which ensures the integrity of all cellular processes including signalling, communication, homeostasis and development.