Membrane transport systems

膜传输系统

• 批准号: 1113-2007
• 负责人: Fyles, Thomas
• 金额: $ 5.54万
• 依托单位: University of Victoria
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=473438
• 关键词: Membrane; transport; systems

The goal of this research is to design simple chemical systems that reproduce and improve upon the membrane transport functions found in all cellular life. In the last decade, this program has produced a wide array of new compounds and chemical systems that have reproduced many basic functions of natural ion channels. It is now possible to design and prepare synthetic compounds that are as active as natural examples using simplified and rapid syntheses of ion channel candidates through conventional solution and solid-phase synthesis.

这项研究的目标是设计简单的化学系统，复制和改进所有细胞生命中发现的膜运输功能。在过去的十年里，这个程序已经产生了一系列新的化合物和化学系统，这些化合物和化学系统复制了天然离子通道的许多基本功能。现在，通过传统的溶液和固相合成，使用离子通道候选物的简化和快速合成，可以设计和制备与自然例子一样具有活性的合成化合物。