Metal mediated and catalyzed organic synthetic methods

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The objective of the proposed research is to develop and understand a series of novel organic chemical reactions mediated by transition metal complexes or catalyzed by either transition metal complexes or main group compounds. The goals include the development of types of carbon-carbon bond forming reactions not normally readily accomplished by traditional organic chemical processes (i.e., the pattern of reactivity is inverted relative to most organic compounds), and to prepare and use compounds that could not normally exist if it were not for the presence of the metal unit. In particular the proposed indium, rhodium, and iridium catalyzed allylation reactions, in conjunction with other catalytic reactions, are designed for being catalytic methods of giving this inverted pattern of reactivity. The proposed alkynedicobalt complexes are designed to make possible the use of compounds that could not be isolated if not for the cobalt.