Motion of the charged droplets and ions in mass spectrometers

带电液滴和离子在质谱仪中的运动

• 批准号: 445591-2012
• 负责人: Ashgriz, Nasser
• 金额: $ 3.13万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=535945
• 关键词: Motion; charged; droplets; ions; mass

This proposal is aimed at improving sensitivity of mass spectrometers (MS). This will be achieved by modeling the ion flow through various parts of a MS which are responsible for ion formation and transportation. The objective is to improve the ion current in order to minimize losses and maximize quality. We will use a combination of gas flow drag and electric field to model the ionic motion. We anticipate significant improvement in the signal-to-noise ratio, thereby enabling substantially lower levels of quantization. We also anticipate development of new technologies in the mass spectrometry based on the ion motion control, using both flow and electric field.

该建议旨在提高质谱仪(MS)的灵敏度。这将通过对MS中负责离子形成和传输的不同部分的离子流动进行建模来实现。其目的是改善离子电流，以便最大限度地减少损耗和最大限度地提高质量。我们将使用气流阻力和电场的组合来模拟离子运动。我们预计信噪比将显著提高，从而实现更低的量化水平。我们还展望了基于离子运动控制的、同时利用流动和电场的质谱学新技术的发展。