Bioengineering imaging by near infrared transient radiative heat transfer

目标：该项目的目的是改进一种旨在利用近红外断层扫描预测肿瘤检测的方法。这个项目包含在一个更一般的目标中，目的是阐述一种新的人体成像技术，这种技术更敏感(分辨率更高)，并且没有副作用(来源在近红外)。总而言之，正是对激光的反应进行分析，激光发射的频率不同于与X射线相关的频率(即红外线)，它指向整个有机组织，使确定这些组织是否正常成为可能。在这里，我们也想降低检测潜在肿瘤的门槛。这是强制性的，潜在的肿瘤可能会在生长的早期阶段被发现。如果组织的辐射特性随着可疑质量的存在而变化，这将是可能的。 工作：拉瓦尔大学和里昂INSA的早期工作允许开发出一种模型，模拟脉冲单色辐射铅笔与有机物之间的相互作用。在2000至2007年间，为了成功地制定、实施和验证上述模型，已经研究了两种方法。在开发的这个阶段，仍然需要验证，需要考虑更多的应用程序，需要进行更多的分析。此外，还需要进行实验验证来测量特定的通量。最后，为了从这些通量的测量中确定介质的性质，逆方法的发展是至关重要的。 发病率：这项研究将给加拿大人带来实实在在的好处，因为它最终将使人们能够依靠一种更敏感的无害技术来检测癌症肿瘤。

GOAL: The aim of the project is to improve a method aimed at predicting the detection of tumors by use of near infrared tomography. This program is included in a more general aim at elaborating a novel technique for the HUMAN BODY IMAGING that is more sensitive (improved resolution) and free of sides effects (the source being in the near infrared). In summary, it is the analysis of the response of a laser, emitting in a different frequency than that associated with X-rays (i.e. infrared), that is directed throughout organic tissues that makes it possible to determine whether or not these tissues are sane. Here, we also want to lower the threshold of detection of potential tumors. It is mandatory that the potential tumors may be detected at an earlier stage of growth. This will be made possible provided that the radiative properties of the tissues will vary with the presence of a suspect mass. WORK: Earlier work in Laval University and INSA of Lyon permitted to develop a model that simulates the interaction between a pulsed monochromatic pencil of radiation and organic matter. Two methods have been investigated between 2000 and 2007 to successfully formulate, implement, and validate the above-mentioned model. At this stage of the development, validation is still needed, more applications have to be accounted for, and more analyses are required. Experimental validations are moreover needed to measure specific fluxes. Finally, the developement of inverse methods is crucial so as to determine the properties of the media from the measurements of theses fluxes. INCIDENCE: This research will generate concrete benefits to Canadians as it will ultimately enable the people to rely on a non-harmful technology that is more sensitive to detect cancerous tumors.