Multidimensional motion correction in MRI

摘要：对象运动仍然是磁共振成像中的一个重要问题--随意的或生理的运动会导致图像中的模糊和其他伪影。目前有一种被称为“导航仪”的技术，它在图像获取过程中使用，可以校正一维中的运动。我们团队一直致力于开发一种三维“导航仪”，以允许同时检测所有维度的运动。我们将面临和努力克服的一些挑战包括：能够确保新的导航器能够足够快地制造出来，从而不会干扰图像的获取，并开发出在大脑和心脏成像期间使用它们的技术。这项研究将包括许多步骤，从优化获取导航仪的方式开始，验证导航仪的准确性，并在磁共振扫描仪上实施。 意义：这项工作的成功将带来使用基于磁共振的技术实时监测和纠正头部、心脏和其他器官的三维平移和旋转的能力；这是以前从未展示过的。加速三维导航技术的成功实施和验证有望对大脑和心脏磁共振成像产生立竿见影的影响。

Summary: Subject motion remains an important problem in magnetic resonance (MR) imaging - voluntary or physiologic motion causes blurring and other artifacts in the images. Currently there is a technique called a "navigator" that is used during the acquisition of the image that can correct for motion in one dimension. Our group has been working on developing a three-dimensional "navigator" to allow motions in all dimensions to be detected simultaneously. Some of the challenges we will face and work to overcome include the ability to ensure that the new navigators can be made fast enough so as not to interfere with the acquisition of the image and to develop techniques for using them during imaging of brain and heart. The research will include many steps, starting with an optimization of the way the navigators are acquired, verification of the accuracy and implementation on the MRI scanners. Significance: The success of this work will lead to the ability to monitor and correct for three-dimensional translation and rotation of the head, heart, and other organs in real time using an MR-based technique; this has not been demonstrated previously. The successful implementation and verification of the accelerated three-dimensional navigator technique promises to have immediate impact on brain and heart MR imaging.