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Advancing antigen-specific nanomedicines for the treatment of autoimmune disease: mechanistic and translational studies.

Advancing antigen-specific nanomedicines for the treatment of autoimmune disease: mechanistic and translational studies.
推进抗原特异性纳米药物治疗自身免疫性疾病:机制和转化研究。
批准号:
332902
负责人:
Santamaria Pere
金额:
$249.45万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-09-01 至 2022-09-01

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中文摘要
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英文摘要
The current proposal is founded on the discovery of a new approach for the treatment of autoimmune disease (occurring when the white blood cells of our immune system mistakenly recognize and attack natural components of our own tissues). Traditionally,
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会议论文
Epigenetic and transcriptional regulation of a novel T-follicular helper (TFH)-to-T-regulatory type-1 (TR1) cell differentiation pathway
  • 批准号:
    461070
  • 项目类别:
    Operating Grants
  • 资助金额:
    $76.91万
  • 财政年份:
    2022
  • 负责人:
    Santamaria Pere
  • 依托单位:
Structural determinants and mechanisms underlying the Major Histocompatibility Complex Class II gene-linked resistance to autoimmune diabetes
  • 批准号:
    461072
  • 项目类别:
    Operating Grants
  • 资助金额:
    $77.47万
  • 财政年份:
    2022
  • 负责人:
    Santamaria Pere
  • 依托单位:
Mechanisms underlying the formation of autoantigen-specific regulatory networks in vivo
  • 批准号:
    342027
  • 项目类别:
    Operating Grants
  • 资助金额:
    $78.25万
  • 财政年份:
    2016
  • 负责人:
    Santamaria Pere
  • 依托单位:
T-cell tolerance versus the genetic resistance to spontaneous autoimmune diabetes in mice.
  • 批准号:
    304696
  • 项目类别:
    Operating Grants
  • 资助金额:
    $73.97万
  • 财政年份:
    2014
  • 负责人:
    Santamaria Pere
  • 依托单位:
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