T-cell tolerance versus the genetic resistance to spontaneous autoimmune diabetes in mice.
T-cell tolerance versus the genetic resistance to spontaneous autoimmune diabetes in mice.
批准号:
304696
负责人:
Santamaria Pere
金额:
$73.97万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-03-01 至 2019-03-01
中文摘要
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英文摘要
Type 1 diabetes (T1D) results from immune dysregulation (autoimmunity) leading to destruction of the insulin-producing cells of the pancreas (beta cells) by killer white blood cells. Susceptibility to T1D is genetically determined, but the mechanisms are
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