T-cell tolerance versus the genetic resistance to spontaneous autoimmune diabetes in mice
T-cell tolerance versus the genetic resistance to spontaneous autoimmune diabetes in mice
批准号:
199091
负责人:
Santamaria Pere
金额:
$55.18万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2015-03-01
中文摘要
胰岛素依赖型或1型糖尿病(T1D)是由于免疫失调(自身免疫)导致胰腺的胰岛素生成细胞(β细胞)被β细胞杀手白细胞破坏。对T1D的易感性是遗传的
英文摘要
Insulin-dependent or type 1 diabetes mellitus (T1D) results from immune dysregulation (autoimmunity) leading to destruction of the insulin-producing cells of the pancreas (beta cells) by beta cell-killer white blood cells. Susceptibility to T1D is genetic
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海外基金