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Epigenetic and transcriptional regulation of a novel T-follicular helper (TFH)-to-T-regulatory type-1 (TR1) cell differentiation pathway

Epigenetic and transcriptional regulation of a novel T-follicular helper (TFH)-to-T-regulatory type-1 (TR1) cell differentiation pathway
新型滤泡辅助性 T (TFH) 至 T 调节型 1 (TR1) 细胞分化途径的表观遗传和转录调控
批准号:
461070
负责人:
Santamaria Pere
金额:
$76.91万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01

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A few years ago, we discovered a new class of drugs, based on the use of tiny particles about a billion times smaller than a golf ball (a nanomedicine), that can treat diseases caused by mis-directed attacks of our own organs (e.g., the pancreatic beta ce
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Structural determinants and mechanisms underlying the Major Histocompatibility Complex Class II gene-linked resistance to autoimmune diabetes
  • 批准号:
    461072
  • 项目类别:
    Operating Grants
  • 资助金额:
    $77.47万
  • 财政年份:
    2022
  • 负责人:
    Santamaria Pere
  • 依托单位:
Mechanisms underlying the formation of autoantigen-specific regulatory networks in vivo
  • 批准号:
    342027
  • 项目类别:
    Operating Grants
  • 资助金额:
    $78.25万
  • 财政年份:
    2016
  • 负责人:
    Santamaria Pere
  • 依托单位:
Advancing antigen-specific nanomedicines for the treatment of autoimmune disease: mechanistic and translational studies.
  • 批准号:
    332902
  • 项目类别:
    Operating Grants
  • 资助金额:
    $249.45万
  • 财政年份:
    2015
  • 负责人:
    Santamaria Pere
  • 依托单位:
T-cell tolerance versus the genetic resistance to spontaneous autoimmune diabetes in mice.
  • 批准号:
    304696
  • 项目类别:
    Operating Grants
  • 资助金额:
    $73.97万
  • 财政年份:
    2014
  • 负责人:
    Santamaria Pere
  • 依托单位:
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