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Immunoregulatory nanovaccines: Optimization of physical, chemical, pharmacokinetic and immunological properties for bench-to-bedside translation

Immunoregulatory nanovaccines: Optimization of physical, chemical, pharmacokinetic and immunological properties for bench-to-bedside translation
免疫调节纳米疫苗:优化物理、化学、药代动力学和免疫学特性,实现实验室到临床的转化
批准号:
222880
负责人:
Santamaria Pere
金额:
$21.11万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-10-01 至 2013-10-01
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中文摘要
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英文摘要
The current proposal is founded on the discovery of a new paradigm in the treatment of type 1 diabetes (caused by the white blood cells of the immune system) of potential groundbreaking significance. Traditionally, vaccines have been used to expand white
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Epigenetic and transcriptional regulation of a novel T-follicular helper (TFH)-to-T-regulatory type-1 (TR1) cell differentiation pathway
  • 批准号:
    461070
  • 项目类别:
    Operating Grants
  • 资助金额:
    $76.91万
  • 财政年份:
    2022
  • 负责人:
    Santamaria Pere
  • 依托单位:
Structural determinants and mechanisms underlying the Major Histocompatibility Complex Class II gene-linked resistance to autoimmune diabetes
  • 批准号:
    461072
  • 项目类别:
    Operating Grants
  • 资助金额:
    $77.47万
  • 财政年份:
    2022
  • 负责人:
    Santamaria Pere
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Mechanisms underlying the formation of autoantigen-specific regulatory networks in vivo
  • 批准号:
    342027
  • 项目类别:
    Operating Grants
  • 资助金额:
    $78.25万
  • 财政年份:
    2016
  • 负责人:
    Santamaria Pere
  • 依托单位:
Advancing antigen-specific nanomedicines for the treatment of autoimmune disease: mechanistic and translational studies.
  • 批准号:
    332902
  • 项目类别:
    Operating Grants
  • 资助金额:
    $249.45万
  • 财政年份:
    2015
  • 负责人:
    Santamaria Pere
  • 依托单位:
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