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Kinetic evolution of a diabetogenic CD8+ T-cell response

Kinetic evolution of a diabetogenic CD8+ T-cell response
致糖尿病 CD8 T 细胞反应的动力学进化
批准号:
209649
负责人:
Santamaria Pere
金额:
$56.55万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-09-01 至 2015-09-01

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中文摘要
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英文摘要
Type 1 Diabetes (T1D) results from immune dysregulation (autoimmunity) leading to destruction of the insulin-producing cells of the pancreas (ß cells) by specific white blood cells (ß cell-killer lymphocytes). It has been known for quite some time that de
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Mechanisms underlying the formation of autoantigen-specific regulatory networks in vivo
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