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Integrated in vivo and ex vivo characterization of cerebrovascular dysfunction and its consequences in transgenic models of Alzheimer's disease

Integrated in vivo and ex vivo characterization of cerebrovascular dysfunction and its consequences in transgenic models of Alzheimer's disease
阿尔茨海默病转基因模型中脑血管功能障碍及其后果的体内和离体综合表征
批准号:
171047
负责人:
Bedell Barry J
金额:
$37.01万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2011-09-01

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中文摘要
翻译
阿尔茨海默氏病(AD)是已知的影响在大脑中的血管。越来越多的证据表明,血管异常在AD的发展和进展中起着重要作用。因此,靶向AD相关疾病的新药
英文摘要
Alzheimer's disease (AD) is known to affect the blood vessels in the brain. Growing evidence points to the fact that abnormalities of the blood vessels play a major role in the development and progression of AD. As such, new drugs which target AD-associat
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Cerebrovascular pathophysiology in mouse models of Alzheimer's disease
Multi-parametric imaging studies of novel therapeutic agents in rodent models of glioma
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