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Smart home-cage for combined optogenetics and electrophysiology

Smart home-cage for combined optogenetics and electrophysiology
结合光遗传学和电生理学的智能家居笼
批准号:
493868-2016
负责人:
Gosselin, Benoit
金额:
$1.09万
依托单位:
依托单位国家:
加拿大
项目类别:
Idea to Innovation
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-01-01 至 2017-12-31

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中文摘要
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英文摘要
We have previously developed the first fully wireless head mounted device to combine optical stimulation for optogenetics and electrophysiological recording within a single device. This system enables to activate and track brain activity in freely moving rodents in real time using a new microelectronic design and dedicated signal processing algorithms recently invented by Dr Gosselin at ULAVAL. This is the only tool to enable circuits' analysis in awake and behaving rodents, with high spatial resolution and at millisecond time scale, through large-scale electrophysiology technology combined with optogenetic capabilities, which is key for research. The researchers from all around the world need such a tool to advance knowledge of brain functions and to develop novel therapeutics against brain diseases.
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