Fabrication of hollow micro-needle array for screening allergies

用于筛查过敏的空心微针阵列的制备

• 批准号: 505276-2016
• 负责人: Cui, Bo
• 金额: $ 1.82万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=609622
• 关键词: Fabrication; hollow; micro; needle; array

For transdermal drug delivery, skin fluid and blood extraction, the conventional stainless steel needle causes pain to the patients and is hard to be integrated with other medical devices at point-of-care-test fields. One solution to those limitations is micro-needle array because of its minimal invasive area/depth causing less pain and ability to be integrated with other micro-devices. Moreover, no cases of infection by micro-needles have been reported so far . Such micro-needles can be solid or hollow with an approximate length of 50-900 µm and an external diameter of not more than 300 µm.

对于经皮给药、皮肤液体和血液提取，传统的不锈钢针给患者带来疼痛，并且难以在现场护理测试领域与其他医疗设备集成。这些限制的一个解决方案是微针阵列，因为其最小的侵入面积/深度导致更少的疼痛，并且能够与其他微型设备集成。此外，迄今为止，还没有关于微型针头感染病例的报告。这种微针可以是实心或空心的，长度约为50-900 µm，外径不超过300 µm。