Radicals at Interfaces: Understanding and Exploiting the Physical Behaviour of Radicals on the Surfaces of Biological and Bulk Materials

界面处的自由基：了解和利用生物和散装材料表面上自由基的物理行为

• 批准号: RGPIN-2015-05488
• 负责人: DiLabio, Gino
• 金额: $ 2.55万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632416
• 关键词: Radicals; Interfaces; Understanding; Exploiting; Physical

Chemical species known as radicals tend to be highly reactive because they have one or more unpaired electrons.  In living systems, oxygen-centred radicals are present because of the respiration of oxygen.  These oxygen-centred radicals are extremely damaging to biological materials such as proteins because they initiate chemical reactions that destroy biomaterial function and consequently induce disease states.  In high-technology applications, radicals often serve as defect centres that inhibit the performance of electronic devices such as computer chips by acting as charge-traps.  In both of these diverse example systems, radicals are ubiquitous.

被称为自由基的化学物种往往具有高反应性，因为它们具有一个或多个未配对的电子设备。在生物系统中，由于氧气的呼吸，存在以氧气为中心的自由基。这些以氧气为中心的自由基对生物材料（例如蛋白质）极大破坏，因为它们启动了破坏生物材料功能并因此诱导疾病状态的化学反应。在高科技应用中，激进分子通常用作缺陷中心，这些缺陷中心通过充当电荷陷阱来抑制电子设备（例如计算机芯片）的性能。在这两个潜水员示例系统中，自由基无处不在。