Smart Brain-Microsystem Interfaces for Efficient Diagnostic and Treatment of Neurodegenerative diseases

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Nowadays, neurodegenerative diseases are behind most neural central system dysfunctions, where an estimated 26% of population suffers from some of these brain disorders (Brain & Behavior Research Foundation), and where little can be done to guaranty accurate diagnostics, and to secure efficient treatment. These circumstances motivated researchers to propose advanced implantable brain-microsystem interfaces in a good standing to facilitate access to various brain regions for both diagnostic and treatment purposes. Despite significant progresses in the development of biointerfaces, further synergism is needed for real-time reliable diagnostics of dysfunctions and efficient treatment procedures. Monitoring neural cell and neurotransmitter activities, and neuromodulate neural functions require design, assembly, and packaging processes of advanced microsystems.