Development of novel optical force sensors for applications in helmet and concussion research
开发用于头盔和脑震荡研究的新型光学力传感器
基本信息
- 批准号:435921-2013
- 负责人:
- 金额:$ 1.82万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2017
- 资助国家:加拿大
- 起止时间:2017-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Millions of children, adolescents and adults participate in sports that carry with them increased risk of head and brain injury. In North America, millions of people sustain brain injury each year, resulting in societal costs in $Billions. In many sports, helmet use has eliminated fatal head injuries, but these helmets have not been effective at reducing concussion incidence. To prevent concussion, a clear understanding of the mechanics of head impact (force rates, magnitudes and durations; and accelerations) and its connection with concussion must be understood. This understanding is currently incomplete and, therefore, helmet designers are currently unable to design helmets that prevent concussion. The long term potential of this program to improve our understanding of helmet performance, injury prevention and to improve helmet design is high. The proposed program will lead to the first sensor system that can measure force at the helmet/head interface of test-dummy heads used in helmet and concussion research. The system will allow the first dynamic measurements of temporal forces (forces through time) during helmeted impacts. The novel sensor system and the first temporal measurements of helmet force will be two original, high impact contributions to helmet science. The proposed study of forces during helmeted impact will provide the first experimental data into whether force magnitude, duration and location correlate with injury metrics and could potentially lead to improved injury metrics that incorporate both forces and accelerations. The proposed study of forces during impact with simulated helmet/head fit scenarios will provide the first quantified approach to understanding how forces and injury metrics vary with helmet fit. Data on all of the above aspects is lacking in the current literature and therefore these will be high impact contributions. With improved understanding of the mechanics of head protection with helmets, head injury and concussion, helmet designers could design the next generation of helmets that prevent both fatal head injuries and non fatal injuries including concussion, which would in turn reduce concussion incidence in all segments of the population engaged in sport.
数以百万计的儿童、青少年和成年人参加的运动增加了头部和大脑受伤的风险。在北美,每年有数百万人遭受脑损伤,导致数十亿美元的社会成本。在许多运动中,头盔的使用已经消除了致命的头部损伤,但这些头盔并不能有效地减少脑震荡的发生率。为了防止脑震荡,必须清楚地了解头部撞击的力学(力的速率,幅度和持续时间;和加速度)及其与脑震荡的联系。这种理解目前是不完整的,因此,头盔设计者目前无法设计防止脑震荡的头盔。这个项目的长期潜力是提高我们对头盔性能、伤害预防和改进头盔设计的理解。拟议的计划将导致第一个传感器系统,可以测量力的头盔/头部接口的测试假人头部在头盔和脑震荡的研究。该系统将允许首次动态测量头盔撞击期间的时间力(时间力)。新的传感器系统和头盔力的第一次时间测量将是对头盔科学的两个原创性的、高影响力的贡献。拟议的头盔冲击力研究将提供第一个实验数据,以确定力的大小,持续时间和位置是否与伤害指标相关,并可能导致改进的伤害指标,包括力和加速度。在模拟头盔/头部贴合场景的冲击过程中,拟议的力研究将提供第一个量化的方法来了解力和伤害指标如何随头盔贴合度而变化。目前的文献中缺乏关于上述所有方面的数据,因此这些将是高影响力的贡献。随着对头盔头部保护机制、头部损伤和脑震荡的进一步了解,头盔设计者可以设计出下一代头盔,既防止致命的头部损伤,也防止包括脑震荡在内的非致命损伤,这反过来又会减少从事体育运动的所有人群中脑震荡的发生率。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Dennison, Christopher其他文献
Investigating the role of zinc and copper binding motifs of trafficking sites in the cyanobacterium Synechocystis PCC 6803.
- DOI:
10.1021/bi400492t - 发表时间:
2013-10-01 - 期刊:
- 影响因子:2.9
- 作者:
Badarau, Adriana;Basle, Arnaud;Firbank, Susan J.;Dennison, Christopher - 通讯作者:
Dennison, Christopher
Regulation of protein function: Crystal packing interfaces and conformational dimerization
蛋白质功能的调节:晶体堆积界面和构象二聚化
- DOI:
10.1021/bi800125h - 发表时间:
2008-06-24 - 期刊:
- 影响因子:2.9
- 作者:
Crowley, Peter B.;Matias, Pedro M.;Dennison, Christopher - 通讯作者:
Dennison, Christopher
FutA2 is a ferric binding protein from Synechocystis PCC 6803
- DOI:
10.1074/jbc.m709907200 - 发表时间:
2008-05-02 - 期刊:
- 影响因子:4.8
- 作者:
Badarau, Adriana;Firbank, Susan J.;Dennison, Christopher - 通讯作者:
Dennison, Christopher
The influence of protein folding on the copper affinities of trafficking and target sites
- DOI:
10.1039/c2dt32166a - 发表时间:
2013-01-01 - 期刊:
- 影响因子:4
- 作者:
Allen, Stephen;Badarau, Adriana;Dennison, Christopher - 通讯作者:
Dennison, Christopher
Important Structural Features of Thiolate-Rich Four-Helix Bundles for Cu(I) Uptake and Removal.
- DOI:
10.1021/acs.inorgchem.2c04490 - 发表时间:
2023-05-01 - 期刊:
- 影响因子:4.6
- 作者:
Lee, Jaeick;Dalton, Rosemary A.;Basle, Arnaud;Vita, Nicolas;Dennison, Christopher;Subtilis, Bacillus - 通讯作者:
Subtilis, Bacillus
Dennison, Christopher的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Dennison, Christopher', 18)}}的其他基金
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
- 批准号:
RGPIN-2018-04253 - 财政年份:2022
- 资助金额:
$ 1.82万 - 项目类别:
Discovery Grants Program - Individual
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
- 批准号:
RGPIN-2018-04253 - 财政年份:2021
- 资助金额:
$ 1.82万 - 项目类别:
Discovery Grants Program - Individual
Biomedical Instrumentation
生物医学仪器
- 批准号:
CRC-2017-00050 - 财政年份:2021
- 资助金额:
$ 1.82万 - 项目类别:
Canada Research Chairs
Towards an advanced head surrogate for blunt impact assessment in defense injury scenarios
寻找一种先进的头部替代物,用于防御伤害场景中的钝器撞击评估
- 批准号:
554461-2020 - 财政年份:2021
- 资助金额:
$ 1.82万 - 项目类别:
Alliance Grants
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
- 批准号:
RGPIN-2018-04253 - 财政年份:2020
- 资助金额:
$ 1.82万 - 项目类别:
Discovery Grants Program - Individual
Towards an advanced head surrogate for blunt impact assessment in defense injury scenarios
寻找一种先进的头部替代物,用于防御伤害场景中的钝器撞击评估
- 批准号:
554461-2020 - 财政年份:2020
- 资助金额:
$ 1.82万 - 项目类别:
Alliance Grants
Biomedical Instrumentation
生物医学仪器
- 批准号:
CRC-2017-00050 - 财政年份:2020
- 资助金额:
$ 1.82万 - 项目类别:
Canada Research Chairs
Biomedical Instrumentation
生物医学仪器
- 批准号:
CRC-2017-00050 - 财政年份:2019
- 资助金额:
$ 1.82万 - 项目类别:
Canada Research Chairs
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
- 批准号:
RGPIN-2018-04253 - 财政年份:2019
- 资助金额:
$ 1.82万 - 项目类别:
Discovery Grants Program - Individual
Novel instrumentation and models for biomechanical assessment of engineered protection devices
用于工程保护装置生物力学评估的新型仪器和模型
- 批准号:
RGPIN-2018-04253 - 财政年份:2018
- 资助金额:
$ 1.82万 - 项目类别:
Discovery Grants Program - Individual
相似国自然基金
Novel-miR-1134调控LHCGR的表达介导拟
穴青蟹卵巢发育的机制研究
- 批准号:
- 批准年份:2025
- 资助金额:10.0 万元
- 项目类别:省市级项目
novel-miR75靶向OPR2,CA2和STK基因调控人参真菌胁迫响应的分子机制研究
- 批准号:82304677
- 批准年份:2023
- 资助金额:30.00 万元
- 项目类别:青年科学基金项目
海南广藿香Novel17-GSO1响应p-HBA调控连作障碍的分子机制
- 批准号:82304658
- 批准年份:2023
- 资助金额:30 万元
- 项目类别:青年科学基金项目
白术多糖通过novel-mir2双靶向TRADD/MLKL缓解免疫抑制雏鹅的胸腺程序性坏死
- 批准号:
- 批准年份:2021
- 资助金额:30 万元
- 项目类别:青年科学基金项目
novel_circ_001042/miR-298-5p/Capn1轴调节线粒体能量代谢在先天性肛门直肠畸形发生中的作用机制研究
- 批准号:
- 批准年份:2021
- 资助金额:55 万元
- 项目类别:面上项目
novel-miR-59靶向HMGAs介导儿童早衰症细胞衰老的作用及机制研究
- 批准号:
- 批准年份:2021
- 资助金额:58 万元
- 项目类别:面上项目
novel_circ_008138/rno-miR-374-3p/SFRP4调控Wnt信号通路参与先天性肛门直肠畸形发生的分子机制研究
- 批准号:82070530
- 批准年份:2020
- 资助金额:55 万元
- 项目类别:面上项目
miRNA-novel-272通过靶向半乳糖凝集素3调控牙鲆肠道上皮细胞炎症反应的机制研究
- 批准号:32002421
- 批准年份:2020
- 资助金额:24.0 万元
- 项目类别:青年科学基金项目
m6A修饰介导的lncRNA WEE2-AS1转录后novel-pri-miRNA剪切机制在胶质瘤恶性进展中的作用研究
- 批准号:
- 批准年份:2020
- 资助金额:55 万元
- 项目类别:面上项目
miRNA/novel_167靶向抑制Dmrt1的表达在红鳍东方鲀性别分化过程中的功能研究
- 批准号:31902347
- 批准年份:2019
- 资助金额:25.0 万元
- 项目类别:青年科学基金项目
相似海外基金
Development of a Colorimetric Sensor for Detection of Cerebrospinal Fluid Leaks
开发用于检测脑脊液泄漏的比色传感器
- 批准号:
10602859 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Development of beam-offset optical coherence tomography
光束偏移光学相干断层扫描技术的发展
- 批准号:
10666910 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Supplement to Support the Development of a New Multiplexed Imaging Tool using Raman Spectroscopy for Breast Cancer
支持开发使用拉曼光谱治疗乳腺癌的新型多重成像工具的补充材料
- 批准号:
10839117 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Investigating mechanisms of tissue polarity during development and disease
研究发育和疾病过程中组织极性的机制
- 批准号:
10751262 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Establishing the design and development of novel crystalline-amorphous hybrid optical coatings for precision measurements and frequency standards
建立用于精密测量和频率标准的新型晶体-非晶混合光学涂层的设计和开发
- 批准号:
ST/X004856/1 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Research Grant
Development of a sample preparation protocol for 3D kidney ultrastructural analysis and immunolabeling by light microscopy
开发用于 3D 肾脏超微结构分析和光学显微镜免疫标记的样品制备方案
- 批准号:
10760947 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Super-multiplex optical imaging: development of novel spectroscopy and probes to illuminate complex biomedicine
超级多重光学成像:开发新型光谱学和探针来阐明复杂的生物医学
- 批准号:
10622905 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Grem1 and Grem2 in embryonic ovary development
Grem1 和 Grem2 在胚胎卵巢发育中的作用
- 批准号:
10584129 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Establishing the design and development of novel crystalline-amorphous hybrid optical coatings for precision measurements and frequency standards
建立用于精密测量和频率标准的新型晶体-非晶混合光学涂层的设计和开发
- 批准号:
ST/X004740/1 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别:
Research Grant
Streamlined development of an IND with the silica nanocapsule loaded with Cas9 genome editors to disrupt the dominant BEST1 mutant allele
使用装载有 Cas9 基因组编辑器的二氧化硅纳米胶囊简化 IND 的开发,以破坏占主导地位的 BEST1 突变等位基因
- 批准号:
10668168 - 财政年份:2023
- 资助金额:
$ 1.82万 - 项目类别: