Automated Peptide Synthesizer System for Accelerating discovery of Nanomaterials, Sensors, and Bioactive Compounds

用于加速纳米材料、传感器和生物活性化合物发现的自动肽合成器系统

• 批准号: RTI-2019-00009
• 负责人: Alarcon, Emilio
• 金额: $ 10.69万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=643685
• 关键词: Automated; Peptide; Synthesizer; System; Accelerating

We are requesting the purchase of an Automated Peptide Synthesizer (APS) capable of preparing up to 9 20-mer peptides over 12 h. A system that is a unique tool for accelerating the discovery of novel materials for tissue engineering & fundamental free radical studies as well as enable the development of peptide-based imaging probes, new radiochemical methods and discovery of the enzymatic cleavage of novel DPP4 peptide sequences and their role in intestinal adaptation to nutrients. As a result, this APS equipment will enhance the impact and expedite the development of diverse areas of natural science and engineering research in Canada including, but not limited to, nanotechnology, biomimetic materials, fundamental physiology, radiochemical labeling of biopolymers and molecular imaging.

我们要求购买一台能够在12小时内制备多达9个20-mer肽的自动肽合成器（APS）。该系统是加速组织工程和基础自由基研究新材料发现的独特工具，也能够开发基于肽的成像探针，新的放射化学方法和发现新型DPP4肽序列的酶切及其在肠道适应营养物质中的作用。因此，这种APS设备将增强影响并加快加拿大自然科学和工程研究的各个领域的发展，包括但不限于纳米技术、仿生材料、基础生理学、生物聚合物的放射化学标记和分子成像。