Regulation of neurite outgrowth by an inhibitor of PI3K signalling.
Regulation of neurite outgrowth by an inhibitor of PI3K signalling.
批准号:
DP110103655
负责人:
Prof Christina Mitchell
金额:
$29.56万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
PIPP is an enzyme which inhibits important cellular functions such as cell maturation. We have shown the amount of PIPP is increased in Alzheimer's disease brains. This project will characterise the mechanisms by which PIPP regulates brain cell function to identify how PIPP may be acting to exacerbate Alzheimer's disease development/progression.
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MTMR4, a regulator of PtdIns(3)P
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财政年份:2009
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依托单位:
Regulation of PtdIns(3,4)P2 signalling by inositol polyphosphate 4-phosphatase-1
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批准号:nhmrc : 491029
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资助金额:$37.2万
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财政年份:2008
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依托单位:
The role of PIPP in cell polarization and proliferation.
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批准号:nhmrc : 436638
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项目类别:NHMRC Project Grants
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资助金额:$35.6万
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依托单位:
Characterization of the FHL protein family
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批准号:nhmrc : 436637
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资助金额:$34.54万
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财政年份:2007
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负责人:Prof Christina Mitchell
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依托单位:
The role of PtdIns(4,5)P2 in cellular responses in Saccharomyces cerevisiae.
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批准号:DP0663923
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项目类别:Discovery Projects
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资助金额:$17.98万
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财政年份:2006
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依托单位:
Characterization of the phosphoinositide 5-phosphatase SKIP.
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依托单位:
Regulation of myotubularin function by the novel 3-phosphatase adapter protein (3-PAP)
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批准号:nhmrc : 400080
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项目类别:NHMRC Project Grants
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资助金额:$32.56万
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财政年份:2006
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依托单位:
The role of the inositol polyphosphate 4-phosphatase in cellular signalling
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批准号:nhmrc : 334083
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资助金额:$30.31万
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财政年份:2005
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依托单位:
Characterization of the 72 kDa inositol polyphosphate 5-phosphatase
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批准号:nhmrc : 284273
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资助金额:$30.28万
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财政年份:2004
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依托单位:
The regulation of signalling molecules in Saccharomyces Cerevisiae by inositol polyphosphate 5-phosphatases
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批准号:DP0345120
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项目类别:Discovery Projects
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资助金额:$17.8万
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财政年份:2003
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依托单位:
SHIP-2 regulation of the actin cytoskeleton
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项目类别:NHMRC Project Grants
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资助金额:$29.36万
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财政年份:2003
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依托单位:
The regulation of PI 3-kinase second messenger molecules, PtdIns(3,4)P2 and PtdIns 3-P.
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批准号:nhmrc : 194404
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项目类别:NHMRC Project Grants
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资助金额:$27.14万
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财政年份:2002
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负责人:Prof Christina Mitchell
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依托单位:
Characterization of 72 and 52 kDa inositol polyphosphate 5-phosphatases: role in vesicular trafficking and cell death
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批准号:nhmrc : 143540
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项目类别:NHMRC Project Grants
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资助金额:$27.21万
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财政年份:2001
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负责人:Prof Christina Mitchell
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依托单位:
CHARACTERISATION OF A NOVEL REGULATOR OF PHOSPHOINOSITIDE 3-KINASE-MEDIATED CELL PROLIFERATION AND PLATELET SIGNALLING
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批准号:nhmrc : 143542
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项目类别:NHMRC Project Grants
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资助金额:$33.35万
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财政年份:2001
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负责人:Prof Christina Mitchell
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依托单位:
Regulation of PtdIns(3,4,5)P3 by inositol polyphosphate 5-phosphatases
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批准号:nhmrc : 124559
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项目类别:NHMRC Project Grants
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资助金额:$13.39万
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负责人:Prof Christina Mitchell
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依托单位:
X-ray crystallography facility (rotating anode generator)
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批准号:nhmrc : 1593
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项目类别:NHMRC Infrastructure Grants
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资助金额:$3.17万
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财政年份:2000
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负责人:Prof Christina Mitchell
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依托单位:
The regulation of PI 3-kinase and 3-position phosphoinositides
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批准号:nhmrc : 990420
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项目类别:NHMRC Project Grants
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资助金额:$20.85万
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财政年份:1999
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负责人:Prof Christina Mitchell
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依托单位:
海外基金