Validation of bulk tank milk sampling strategies and identification of risk factors for Salmonella Dublin in dairies

验证散装罐牛奶采样策略并识别乳制品厂中都柏林沙门氏菌的风险因素

• 批准号: 518064-2017
• 负责人: Dufour, Simon
• 金额: $ 3.47万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=689624
• 关键词: Validation; bulk; tank; milk; sampling

Salmonella Dublin is an emerging pathogen in cattle and humans in the province of Québec since 2011. It causes production losses, illness, and death in dairy cattle and can lead to serious illness in humans. Milk pasteurization is an efficient method for controlling this pathogen in dairy products and, thus, identifying dairy herds infected with S. Dublin is of tremendous importance to ensure that milk from infected herds are not used for production of raw-milk products. Moreover, identifying risk factors leading to introduction of this infection in dairies could help better control this disease. Currently, however, we do not have a diagnostic test that could be used to determined without error if a dairy is infected. The aim of this research is to develop a diagnostic strategy based on the use of multiple imperfect diagnostic tests, conducted at different intervals on bulk milk, a media that is readily collected and available on all dairies in Québec and Canada. The economic and diagnostic efficiency of the different sampling strategies will be compared. Finally, the risk factors that could potentially lead to acquisition of Salmonella Dublin infection in dairies will be identified, so that dairy producers can better prevent introduction of this disease in their herd.

都柏林沙门氏菌是2011年以来在曲梅省牛和人类中出现的一种新病原体。它会导致奶牛的生产损失、疾病和死亡，并可能导致人类患上严重疾病。牛奶巴氏杀菌是控制乳制品中这种病原体的有效方法，因此，确定感染都柏林链球菌的奶牛群对于确保来自受感染奶牛群的牛奶不用于生产生乳制品具有极其重要的意义。此外，确定导致在奶牛场引入这种感染的风险因素可以帮助更好地控制这种疾病。然而，目前，我们还没有一种诊断测试，可以用来准确地确定乳制品是否受到感染。这项研究的目的是制定一项诊断战略，其基础是使用多种不完善的诊断测试，以不同的时间间隔对散装牛奶进行测试，散装牛奶是一种易于收集并可在魁地海省和加拿大所有奶牛场获得的培养基。将比较不同采样策略的经济性和诊断效率。最后，将确定可能导致在奶牛场获得都柏林沙门氏菌感染的风险因素，以便奶牛场生产者能够更好地防止将这种疾病引入其畜群。