Validation of bulk tank milk sampling strategies and identification of risk factors for Salmonella Dublin in dairies

验证散装罐牛奶采样策略并识别乳制品厂中都柏林沙门氏菌的风险因素

• 批准号: 518064-2017
• 负责人: Dufour, Simon
• 金额: $ 0.86万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=719465
• 关键词: Validation; bulk; tank; milk; sampling

Salmonella Dublin is an emerging pathogen in cattle and humans in the province of Québec since 2011. It causes production losses, illness, and death in dairy cattle and can lead to serious illness in humans. Milk pasteurization is an efficient method for controlling this pathogen in dairy products and, thus, identifying dairy herds infected with S. Dublin is of tremendous importance to ensure that milk from infected herds are not used for production of raw-milk products. Moreover, identifying risk factors leading to introduction of this infection in dairies could help better control this disease. Currently, however, we do not have a diagnostic test that could be used to determined without error if a dairy is infected. The aim of this research is to develop a diagnostic strategy based on the use of multiple imperfect diagnostic tests, conducted at different intervals on bulk milk, a media that is readily collected and available on all dairies in Québec and Canada. The economic and diagnostic efficiency of the different sampling strategies will be compared. Finally, the risk factors that could potentially lead to acquisition of Salmonella Dublin infection in dairies will be identified, so that dairy producers can better prevent introduction of this disease in their herd.

都柏林沙门氏菌是魁北克省的牛和人类的新兴病原体。它会导致奶牛的生产损失，疾病和死亡，并可能导致人类的严重疾病。牛奶巴氏杀菌是一种在乳制品中控制这种病原体的有效方法，因此，确定被都柏林S.的乳制牛群非常重要，对于确保被感染的牛奶不用于生产原始乳脂产品。此外，确定导致乳制品引入这种感染的危险因素可以帮助更好地控制这种疾病。但是，目前，如果乳制品感染了乳制品，我们没有可以用来确定无错误的诊断测试。这项研究的目的是基于使用多个不完美的诊断测试来制定诊断策略，该诊断测试以不同的间隔对散装牛奶进行，该测试很容易收集，并在魁北克和加拿大的所有奶牛场上都可以使用。将比较不同采样策略的经济和诊断效率。最后，将确定可能导致乳制品中都柏林感染的危险因素，从而确定乳制品生产者可以更好地防止在其群中引入这种疾病。