Electrophysiology amplifiers and software for Sleep Lab

用于睡眠实验室的电生理学放大器和软件

• 批准号: RTI-2020-00426
• 负责人: Cote, Kimberly
• 金额: $ 10.19万
• 依托单位: Brock University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=693529
• 关键词: Electrophysiology; amplifiers; software; Sleep; Lab

The Sleep Research Laboratory at Brock University is a 3-bedroom facility where we investigate sleep, performance and cognition in humans. The long-term goal of the program of research is to understand the functional role of sleep in waking performance. Dr. Cote built the lab in 2000 with state-of-the-art equipment to record brain activity from multiple scalp sites during sleep and waking states. Recording brain wave activity from 64 sites across the scalp provides a dynamic picture or map of changes in arousal and attention that vary across the day and night. Dr. Cote and her students have published extensively on diverse topics including the effects of sleep loss on brain function and performance, the role of sleep in memory consolidation, cognitive benefits of a nap, consciousness at sleep onset and throughout the night, and quantitative analysis of EEG during sleep and wakefulness as it relates to human performance. ******The equipment used to record sleep and brain activity during waking performance is no longer functional. Replacement of the recording amplifiers is crucial for continuation of the program of research and training of highly qualified personnel. Software updates will also improve the efficiency of research output by providing access to modern analysis routines. This equipment will be used for Dr. Cote's NSERC-funded research which investigates the role of sleep in waking information processing. The most recent research grant (funded 2019-2024) aims to investigate the role of REM and non-REM sleep in emotion processing in particular. We will use highly novel paradigms such as deep sleep enhancement with auditory stimulation. Students at all levels receive highly specialized training in electrophysiology in the context of both sleep and waking cognitive performance. As many Canadians do not get the sleep they need, this research may help people to improve performance (work, scholastic, sport) through optimizing sleep, and may also inform intervention strategies in individuals with sleep, emotion, or behavioural disorders. *****

布洛克大学的睡眠研究实验室是一个三居室的设施，我们在那里研究人类的睡眠，表现和认知。该研究计划的长期目标是了解睡眠在清醒表现中的功能作用。科特博士于2000年建立了这个实验室，配备了最先进的设备，可以记录睡眠和清醒状态下多个头皮部位的大脑活动。通过记录头皮上64个部位的脑电波活动，可以提供一幅关于觉醒和注意力昼夜变化的动态图片或地图。Cote博士和她的学生发表了大量关于不同主题的文章，包括睡眠不足对大脑功能和表现的影响，睡眠在记忆巩固中的作用，午睡的认知益处，睡眠开始时和整个晚上的意识，以及睡眠和清醒期间EEG的定量分析，因为它与人类表现有关。** 用于记录睡眠和清醒时大脑活动的设备不再起作用。更换录音放大器对于继续研究和培训高素质人员的方案至关重要。软件更新还将通过提供现代分析程序来提高研究产出的效率。该设备将用于科特博士的NSERC资助的研究，该研究调查了睡眠在清醒信息处理中的作用。最近的研究资助（资助2019-2024）旨在研究REM和非REM睡眠在情绪处理中的作用。我们将使用高度新颖的范例，如深度睡眠增强与听觉刺激。所有级别的学生在睡眠和清醒认知表现的背景下接受电生理学的高度专业化培训。由于许多加拿大人没有得到他们所需要的睡眠，这项研究可能有助于人们通过优化睡眠来改善表现（工作，学业，运动），也可能为患有睡眠，情绪或行为障碍的人提供干预策略。 *****