Organometallic chemistry and catalysis using 3d metals

用地球上丰富的金属（如铁基催化剂）取代贵金属基均相催化剂吸引了大量的研究兴趣。除了与高丰度相关的低成本之外，地球上丰富的金属可能比其贵金属对应物毒性更小，更环保。此外，地球上丰富的金属可能提供新的反应途径，在贵金属化学中不太普遍。虽然自然界在金属酶中广泛使用地球上丰富的金属进行催化反应，但在人造均相催化系统中，地球上丰富的金属却很少被探索。这项拟议的研究涉及开发基于地球上丰富的金属的新型均相催化剂，用于合成与药物，小分子有机材料和聚合物相关的化合物。目标之一是了解地球上丰富的金属的化学行为，这可能会导致有效催化剂的合理设计和新颖的化学转化。

Replacing noble metal-based homogeneous catalysts with earth-abundant metal counterparts (such as iron-based catalysts) has attracted a lot of research interest. In addition to the low cost associated with the high abundance, earth-abundant metals are potentially less toxic and more environmentally friendly than their noble metal counterparts. Moreover, earth-abundant metals can potentially offer novel reaction pathways that are less prevalent in noble metal chemistry. While Nature uses earth-abundant metals in metalloenzymes extensively toward catalytic reactions, earth-abundant metals are far less explored in manmade homogeneous catalytic systems. This proposed research is concerned with the development of novel homogeneous catalysts based on earth-abundant metals toward the syntheses of compounds that are relevant to pharmaceuticals, small molecule organic materials, and polymers. One of the objectives is to gain understanding of the chemical behavior of earth-abundant metals, which may lead to the rational design of efficient catalysts and novel chemical transformations.