Organometallic chemistry and catalysis using 3d metals

使用 3d 金属的有机金属化学和催化

• 批准号: RGPIN-2019-06576
• 负责人: Song, Datong
• 金额: $ 3.5万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=738982
• 关键词: Organometallic; chemistry; catalysis; using; 3d

Replacing noble metal-based homogeneous catalysts with earth-abundant metal counterparts (such as iron-based catalysts) has attracted a lot of research interest. In addition to the low cost associated with the high abundance, earth-abundant metals are potentially less toxic and more environmentally friendly than their noble metal counterparts. Moreover, earth-abundant metals can potentially offer novel reaction pathways that are less prevalent in noble metal chemistry. While Nature uses earth-abundant metals in metalloenzymes extensively toward catalytic reactions, earth-abundant metals are far less explored in manmade homogeneous catalytic systems. This proposed research is concerned with the development of novel homogeneous catalysts based on earth-abundant metals toward the syntheses of compounds that are relevant to pharmaceuticals, small molecule organic materials, and polymers. One of the objectives is to gain understanding of the chemical behavior of earth-abundant metals, which may lead to the rational design of efficient catalysts and novel chemical transformations.

用土壤丰富的金属对应物（例如基于铁的催化剂）代替贵金属的同质催化剂吸引了很多研究兴趣。除了与高丰度相关的低成本外，与贵族金属同行相比，土壤丰富的金属的毒性更少，对环保的更友好。此外，土壤丰富的金属可能会提供新型的反应途径，而在贵族金属化学中，这种反应途径较少。虽然大自然在金属酶中使用了丰富的金属对催化反应，但在人造同质催化系统中探索了土壤丰富的金属。这项提出的研究涉及基于与药物，小分子有机材料和聚合物相关的化合物合成的新型均质催化剂的发展。其中之一是了解地球量金属的化学行为，这可能导致有效的催化剂和新型化学转化的合理设计。