Organometallic chemistry and catalysis using 3d metals

使用 3d 金属的有机金属化学和催化

• 批准号: RGPIN-2019-06576
• 负责人: Song, Datong
• 金额: $ 3.5万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=738982
• 关键词: Organometallic; chemistry; catalysis; using; 3d

Replacing noble metal-based homogeneous catalysts with earth-abundant metal counterparts (such as iron-based catalysts) has attracted a lot of research interest. In addition to the low cost associated with the high abundance, earth-abundant metals are potentially less toxic and more environmentally friendly than their noble metal counterparts. Moreover, earth-abundant metals can potentially offer novel reaction pathways that are less prevalent in noble metal chemistry. While Nature uses earth-abundant metals in metalloenzymes extensively toward catalytic reactions, earth-abundant metals are far less explored in manmade homogeneous catalytic systems. This proposed research is concerned with the development of novel homogeneous catalysts based on earth-abundant metals toward the syntheses of compounds that are relevant to pharmaceuticals, small molecule organic materials, and polymers. One of the objectives is to gain understanding of the chemical behavior of earth-abundant metals, which may lead to the rational design of efficient catalysts and novel chemical transformations.

用富金属催化剂（如铁基催化剂）取代贵金属基均相催化剂引起了广泛的研究兴趣。除了与高丰度相关的低成本外，地球上丰富的金属可能比贵金属毒性更小，更环保。此外，地球上丰富的金属可能提供在贵金属化学中不太常见的新反应途径。虽然自然界在金属酶中广泛使用富含地球资源的金属进行催化反应，但在人造均相催化系统中，富含地球资源的金属却很少被探索。本研究旨在开发基于地球上丰富的金属的新型均相催化剂，用于合成与药物、小分子有机材料和聚合物相关的化合物。其中一个目标是了解地球上丰富的金属的化学行为，这可能导致合理设计有效的催化剂和新的化学转化。