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Exploiting XtalFluor reagents in organic synthesis and developing new approaches to pentafluorosulfanyl-containing molecules

Exploiting XtalFluor reagents in organic synthesis and developing new approaches to pentafluorosulfanyl-containing molecules
在有机合成中利用 XtalFluor 试剂并开发含五氟硫基分子的新方法
批准号:
572205-2022
负责人:
Paquin, JeanFrançoisJF
金额:
$3.72万
依托单位:
依托单位国家:
加拿大
项目类别:
Alliance Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-01-01 至 2023-12-31

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中文摘要
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英文摘要
The projects described herein aim at the development of new synthetic tools for the preparation of organic compounds, in particular fluorine-containing molecules which are of high interest in pharmaceutical industry, in agrochemistry as well as in material sciences. Specific objectives are: 1) the improvement of the deoxofluorination reaction using OmegaChem's XtalFluor reagents; 2) the discovery of new transformations using OmegaChem's XtalFluor reagents for the synthesis of fluorinated (sulfonyl fluorides) and non-fluorinated compounds (acyl halides); and 3) the development of novel synthetic approaches to pentafluorosulfanyl-containing compounds. Overall, these projects are significant in the context that OmegaChem is continually working to introduce on the market new molecules that can be integrated to the design of more complex structures demonstrating innovative properties and increased efficiency.
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Towards a better understanding of the effect of the pentafluorosulfanyl group on the lipophilicity and acid/base properties of alcohols and amines
  • 批准号:
    571856-2021
  • 项目类别:
    Alliance Grants
  • 资助金额:
    $1.82万
  • 财政年份:
    2022
  • 负责人:
    Paquin, JeanFrançoisJF
  • 依托单位:
海外基金