Strengthening the use of XtalFluor reagents in organic synthesis and novel approaches to pentafluorosulfanyl-containing molecules

本文所述的项目旨在开发新的合成工具，无论是反应还是试剂，用于制备有机化合物，特别是在制药工业，农业化学以及材料科学中具有高度兴趣的含氟分子。具体目标是：1）使用OmegaChem的XtalFluor试剂改进脱氧硫代反应; 2）发现使用OmegaChem的XtalFluor试剂合成氟化化合物（三氟甲基硫醚、三氟甲基醚和单氟烯烃）和非氟化化合物（醛和1，1-二芳基环丙烷）的新转化; 3）开发含五氟硫基化合物的新合成方法。总的来说，这些项目在OmegaChem不断努力向市场推出新分子的背景下具有重要意义，这些新分子可以整合到更复杂结构的设计中，展示创新特性和提高效率。

The projects described herein aim at the development of new synthetic tools, either reactions or reagents, forthe preparation of organic compounds, in particular fluorine-containing molecules which are of high interest inpharmaceutical industry, in agrochemistry as well as in material sciences. Specific objectives are: 1) theimprovement of the deoxofluorination reaction using OmegaChem's XtalFluor reagents; 2) the discovery ofnew transformations using OmegaChem's XtalFluor reagents for the synthesis of fluorinated (trifluoromethylthioethers, trifluoromethyl ethers and monofluoroalkenes) and non-fluorinated compounds (aldehydes and1,1-diarylcyclopropanes); and 3) the development of novel synthetic approaches topentafluorosulfanyl-containing compounds. Overall, these projects are significant in the context thatOmegaChem is continually working to introduce on the market new molecules that can be integrated to thedesign of more complex structures demonstrating innovative properties and increased efficiency.