The role of virulence factors of Clostridium difficile in food animals.
The role of virulence factors of Clostridium difficile in food animals.
批准号:
DP1093891
负责人:
Prof Dena Lyras
金额:
$22.99万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
艰难梭菌引起的疾病在许多国家是一个重大的食品生产、动物和公共卫生问题。许多国家已经分配了特定的动物和人类公共卫生资源,以努力减轻日益严重的流行病。这项申请中提出的研究为了解这种细菌动物菌株的毒力因素提供了一个重要的机会,而人们对此知之甚少。该项目将导致对动物和人类都适用的合理设计的预防和治疗策略,从而阻止艰难梭菌在澳大利亚引起的流行病。
英文摘要
Disease caused by the bacterium Clostridium difficile are a significant food production animal and public health problem in many countries. Specific animal and human public health resources have been allocated in many countries in efforts to mitigate the growing epidemics. The study proposed in this application presents a significant opportunity to learn about the virulence factors of animal strains of this bacterium about which very little is known. This project will lead to rationally designed preventative and treatment strategies that apply to both animals and humans, thereby impeding epidemics caused by C. difficile in Australia.
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