Isomerizations of Isotopically Labeled Hydrocarbons

这项有机和大分子化学基金为雪城大学约翰·鲍德温教授的工作提供了支持。这项工作的重点是简单的有机分子如何经历各种化学反应。这些反应对于基本理解这些分子的动态行为，特别是在实验和理论之间的界面上，是特别重要的。通过制备标记化合物并进行跟踪标记的反应，将获得关于热异构化反应基本类型的新的定量信息。在被研究的体系中有稳定的、同位素标记的简单烃环丙烷、环丁烷、环戊烷、环戊烷、顺式-1,3-戊二烯、顺式-1,3,5-庚三烯、环庚三烯和三个双环烯烃。反应立体化学，动力学，动力学同位素效应和机制将被确定。现有的和新的技术，包括可调谐二极管激光和振动圆二色光谱，将在这些研究中使用。

This grant in Organic and Macromolecular Chemistry provides support for the work of Professor John Baldwin, Syracuse University. The work focuses on how simple organic molecules undergo a variety of chemical reactions. These reactions are particularly important for a fundamental understanding of the dynamic behavior of such molecules, particularly at the interface between experiment and theory. New quantitative information on basic types of thermal isomerization reactions will be obtained by preparing labeled compounds and carrying out reactions which track the labels. Among the systems to be investigated are stable, isotope-labeled versions of the simple hydrocarbons cyclopropane, cyclobutane, cyclopentane, cyclopentane, cis-1,3-pentadiene, cis,cis-1,3,5-heptatriene, cycloheptatriene, and three bicyclic olefins. Reaction stereochemistry, kinetics, kinetic isotope effects, and mechanisms will be determined. Both established and novel techniques, including tunable diode laser and vibrational circular dichroism spectroscopy, will be used in these studies.