Instrumentation for a Biological Sequence and Structure Computation Facility

该奖项为购买计算机和相关硬件和软件提供资金，这些硬件和软件将服务于乔治亚大学一个大型跨学科研究小组的需求。与大学提供的其他设备一起，计算机将使研究人员能够研究各种问题，例如酶结构和DNA序列分析，后者尤其适用于研究植物基因调控。新的计算机将补充和取代过时的现有设备，这些设备既维护费用昂贵，又不足以完成提案中所述的某些任务。计算机的有效使用已经彻底改变了当前生物科学许多领域的实践，并实际上创造了其他领域。蛋白质结构的三维分析和DNA序列数据的比较分析是需要大量使用计算的两个很好的研究例子。新型、更小、更强大的计算机正在迅速发展，这意味着几年前购买的设备现在可能已经过时了。此外，网络设备的发展意味着一台计算机可以满足许多用户的需求，并使偶尔的用户能够使用一台功能相对强大的机器，而这些机器的购买是他们个人无法证明的。

This award provides funds for the aquisition of a computer and related hardware and software that will serve the needs of a large, interdisciplinary group of investigators at the University of Georgia. Together with other equipment to be provided by the University, the computer will allow the investigators to work on a variety of problems such as enzyme structure and DNA sequence analysis, the latter especially as applied to the study of plant gene regulation. The new computer will both complement and supplant dated existing equipment which is both expensive to maintain and inadequate for some tasks described in the proposal. The effective use of computers has revolutionized current practice in many areas of biological science, and has virtually created others. The three-dimensional analysis of protein structure and the comparative analysis of DNA sequence data are two good examples of research that neccesitate extensive use of computation. The rapidity with which new, smaller and more powerful computers are being developed means that equipment purchased as recently as a few years ago may now be obsolete. Moreover, the development of networking devices means that a single computer can serve the needs of many users and give occasional users access to a relatively powerful machine whose purchase they could not justify individually.