Determining the biological significance of allelic sequence variation within the T cell receptor loci
Determining the biological significance of allelic sequence variation within the T cell receptor loci
批准号:
nhmrc : 1067374
负责人:
A/Pr John Miles
金额:
$41.85万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
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英文摘要
T lymphocytes play a pivotal role in the immune system by recognising virus-infected tissue through the use of highly specific T cell receptors (TCRs). This project will investigate the importance of genetic variation in the TCR genes in influencing how we fight infections. Advances in these areas will assist in understanding susceptibility to some autoimmune diseases as well as aiding in the development of new "intelligent" vaccines and individualised therapeutics.
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Using Methods in Genetic Epidemiology to Elucidate the Relationship Between Viral Infection and Risk of Autoimmune Disease
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负责人:A/Pr John Miles
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依托单位:
Defining the molecular and functional features of protective HIV-specific T cells
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依托单位:
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依托单位:
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负责人:A/Pr John Miles
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依托单位:
Investigations into supraphysiologic T cell receptors and T cell agonists.
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财政年份:2012
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负责人:A/Pr John Miles
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依托单位:
The role of long peptide epitopes in antiviral CD8+ T cell recognition.
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批准号:nhmrc : 1021620
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项目类别:Project Grants
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资助金额:$28.98万
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财政年份:2012
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负责人:A/Pr John Miles
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依托单位:
Investigations into the biology and functionality of the human T cell receptor
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批准号:nhmrc : 613664
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项目类别:NHMRC Project Grants
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资助金额:$28.29万
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财政年份:2010
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负责人:A/Pr John Miles
-
依托单位:
Investigations into the architectural and biophysical features of optimal T cell receptor design
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批准号:nhmrc : 496721
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项目类别:Early Career Fellowships
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资助金额:$16.8万
-
财政年份:2008
-
负责人:A/Pr John Miles
-
依托单位:
Investigations into the cytolytic T cell response during Epstein-Barr virus related disease
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批准号:nhmrc : 389937
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项目类别:NHMRC Postgraduate Scholarships
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资助金额:$0.25万
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财政年份:2006
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负责人:A/Pr John Miles
-
依托单位:
Cytotoxic T lymphocyte response to Epstein-Barr virus
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批准号:nhmrc : 339480
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项目类别:NHMRC Postgraduate Scholarships
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资助金额:$2.81万
-
财政年份:2005
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负责人:A/Pr John Miles
-
依托单位:
国内基金
海外基金
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