Microelectronic Biosensor for Neural Tissue Data Collection

这个项目是一个电气工程师 和神经科学家，开发一种新的传感器， 我们研究活体人脑的能力有了很大的提高 以及它是如何工作的。 最终目标是发展一个 芯片，0.3 cm × 0.3 cm，包含16，000个独立电极， 脑细胞的独立记录。 的另一部分 研究是发展技术来保持大脑切片的活力 并与传感器接触，并设计传感器， 在这种环境下不会变质。 测试将在 大脑切片已经作为手术的副产品， 癫痫;传感器数据将被分析，以了解模式如何变化 正常组织和引起癫痫的组织之间的联系， 从而深入了解大脑的正常和异常功能。

This project is a collaborative effort between an electrical engineer and a neuroscientist, to develop a new sensor capable of an order of magnitude improvement in our ability to study living human brain tissue and how it works. The ultimate goal is the development of a chip, .3 cm by .3 cm, containing 16,000 independent electrodes capable of independent recording from brain cells. Another part of the research is the development of techniques to keep brain slices alive and functional in contact with the sensor, and to design a sensor which does not deteriorate in that environment. Tests will be done on brain slices already available as a byproduct of surgery to correct epilepsy; sensor data will be analyzed to see how patterns vary between normal tissue and tissue causing the epilepsy, in order to yield insight into normal and abnormal functioning of the brain.