Two-Dimensional Polymerizations in Supramolecular Assemblies

超分子组装体，如单分子膜、囊泡、扩展双分子膜、铸型双分子膜和小管，是两亲分子的二维阵列。最近引入的聚合这些组件的方法为制备具有特殊性能的新材料提供了一种手段。这些二维聚合反应的本质和组装结构对聚合反应的影响一直知之甚少。然而，我们之前的研究为这些聚合过程提供了有价值的见解。这项研究的目的是加强我们对二维聚合的基本原理的初步了解。具体地说，这项研究将强调以下内容：a)控制均脂和混合脂组件中形成的线形聚合物大小的因素；以及c)确定组件聚合中的交联键频率对侧向脂类扩散速率和二维结构域出现的影响。这些数据将主要针对扩展的双层和泡囊组件确定，预计将为评估二维聚合如何平行或偏离各向同性聚合的既定原理提供基础。这项研究结合了合成化学、仪器表征和表面科学。这有望为二维聚合用于膜等新材料的形成提供合理的基础。

Supramolecular assemblies, e.g. monolayers, vesicles, extended bilayers, cast bilayers, and tubules, are two-dimensional arrays of amphiphiles. The recent introduction of methods to polymerize these assemblies provides a means to prepare new materials with unusual properties. The nature of these two-dimensional polymerizations and the effect of the assembly structure on the polymerization reaction has been poorly understood. However our previous research has provided valuable insights into these polymerization processes. The objective of this research is to enhance our fledgling understanding of the fundamentals of two- dimensional polymerizations. Specifically, this reserch will emphasize the following: a) the factors that control the size of linear polymers formed in homolipid and mixed lipid assemblies; and c) determination of the effect of the frequency of crosslinks in the polymerization of the assemblies on both the rate of lateral lipid diffusion, and the appearance of domains in two-dimensions. These data, to be determined primarily for extended bilayer and vesicle assemblies, are expected to provide a basis to evaluate how two-dimensional polymerizations parallel or deviate from the established principles of isotropic polymerizations. This research combines synthetic chemistry, instrumental characterization, and surface science. It is expected to provide a rational foundation for the use of two-dimensional polymerizations for the formation of new materials, such as membranes.