Acquisition of High Field NMR Spectrometer for Macromolecular Structure

该提案要求资金用于购买高 性能，高场，仪器（质子为500 MHz 观察），将致力于大分子结构 保持战略定力 它将为一小群调查人员提供服务， 耶鲁大学的化学系， 生物结构解析项目 大分子 这些项目涉及一系列主题，包括DNA和RNA 重要的结合蛋白、蛋白质和核酸 核糖体功能，脂质生物合成中重要的蛋白质，以及 对细胞表面识别很重要的分子。

This proposal requests funds for the purchase of a high performance, high field, instrument (500 MHz for proton observation) that will be dedicated to macromolecular structure determination. It will serve a small group of investigators in the chemistry department of Yale University who have ongoing projects directed at structure elucidation of biological macromolecules. These projects span a range of subjects that include DNA and RNA binding proteins, proteins and nucleic acids important in ribosome function, proteins important in lipid biosynthesis, and molecules important to cell surface recognition.