FT/ICR/MS: Technique Development and Non-Biological Applications

在分析和曲面的一般领域， 化学，侧重于傅立叶的持续发展 变换离子回旋共振质谱 工作 有望促进质谱法的发展， 非常重要的分析技术。 该项目解决了外部离子注入的问题， 线性化激励/检测。 理论模型 并计划进行设备建造和测试。 新理论 研究将包括一般光谱方面，并将 聚焦傅里叶变换离子回旋共振（FT/ICR） 质谱分析法来 新的工具开发将包括 离子阱设计和特性的研究， 离子外进样，双通道SWIFT和检测 模块。 将进行新的实验， 从所检测的ICR信号确定ICR轨道半径， 结合实验研究了快速中性 用于不挥发性样品的束离子源和一个双向 用于离子注入的频率扫描。 一些分析和 关于锕系金属络合物的化学应用， 立体化学效应，卡宾的气相碱性， 锇团簇离子化学及其在分析中的应用 的聚合物和电极表面也计划。

The research, in the general area of Analytical and Surface Chemistry, focuses on continued development of Fourier transform ion cyclotron resonance mass spectrometry. The work promises to enhance the development of mass spectrometry, a very important analytical technique. The project tackles the problem of external ion injection and linearized excitation/detection. Both theoretical modelling and equipment building and testing are planned. New theory to be studied will include general spectroscopic aspects, and will focus on Fourier transform ion cyclotron resonance (FT/ICR) mass spectrometry. New instrumental developments will include studies of ion trap design and characterization, ion guides for ion external injection, and dual-channel SWIFT and detection modules. New experiments will be performed to directly determine the ICR orbital radius from the detected ICR signal, together with experiments to study the use of a fast neutral beam ion source for involatile samples and a bilateral frequency sweep for ion injection. Some analytical and chemical applications regarding actinide metal complexes, stereochemical effects, gas-phase basicities of carbenes, osmium cluster ion chemistry and applications to the analysis of polymers and electrode surfaces are also planned.