Spectroscopic Characterization of Order and Disorder in Molecular Assemblies

伊利诺伊大学厄巴纳分校的Bohn教授将使用独特的基于激光的综合光学结构测量方法来监测单分子薄膜组件的结构，该项目由分析和表面化学项目支持。这项工作的目的是更好地描述通过Langmuir-Blodgett沉积或自组装方法制备的分子组装的取向分布。将开发三种实验方法。首先，荧光各向异性和线性二色性测量将以高灵敏度应用于静态单层。其次，在直流电场扰动下，将表征组装的顺序。第三，将通过监测对可变频率电场扰动的光学响应来检测薄层的动态响应。本项目开发的波导光学探针方法为表征这些重要分子组装中的顺序提供了独特的结构能力。测定单分子薄膜的有序度是本研究项目的目标，该研究项目由分析和表面化学项目支持。详细了解这些薄膜材料的结构对改进生物活性传感器和痕量分离方法的设计至关重要，并可能影响改进腐蚀涂层的发展。

Unique laser-based measurements in integrated optical structures will be used by Professor Bohn of the University of Illinois-Urbana to monitor the structure of monomolecular thin film assemblies, in this project supported by the Analytical and Surface Chemistry program. The goal of this work is to provide a better description of the orientational distribution of molecular assemblies prepared by Langmuir-Blodgett deposition or by self-assembly methods. Three experimental approaches will be developed. First, fluorescence anisotropy and linear dichroism measurements will be applied to static monolayers at high sensitivity. Second, the order of the assembly will be characterized under dc electric field perturbation. Third, the dynamic response of the thin layer will be examined by monitoring optical response to variable frequency electric field perturbations. The waveguide optical probe methods developed in this project provide a unique structural capability for characterizing order in these important molecular assemblies. %%% Determination of the degree of order in monomolecular thin films is the goal of this research project supported by the Analytical and Surface Chemistry program. A detailed understanding of the structure of these thin film materials is crucial to the design of improved bioactive sensors and trace separation methods, and may impact the development of improved corrosion coatings.