Heavy Metal Chemistry Goes Nuclear: Radioactive Rhenium and Terbium Agents

该项目的目的是在放射性金属的生物无机化学的基本知识方面取得根本性进展，这些放射性金属有可能在未来用作放射性药物。生产Re和Tb的放射性同位素的技术进步增加了将这些放射性核素用作放射性药物的可行性，但它们的使用需要在其基础配位化学方面有新的基本知识。该项目将开发合成放射性Re和Tb络合物的新方法。该项目的成果将是更好地理解配位化学，这是今后将其转化为新的放射性药物所必需的。

This project aims to make fundamental advances in the basic knowledge of the bioinorganic chemistry of radioactive metals that have the potential to be used in the future as radioactive drugs. Technological advances in the production of radioactive isotopes of rhenium and terbium have increased the feasibility of using these radionuclides as radioactive drugs, but their use requires new basic knowledge in their fundamental coordination chemistry. This project will develop new ways to synthesise radioactive rhenium and terbium complexes. The outcomes of this project will be an improved understanding of the coordination chemistry rhenium and terbium which is required to inform their future translation to new radiopharmaceuticals.